ISBN: 9783527318674

By N. Sewald. With peptides playing such a valuable role in the body, the need for a modern and scientifically up-to-date advanced textbook is critical for both students and teachers. Nor… Mehr…

By N. Sewald. With peptides playing such a valuable role in the body, the need for a modern and scientifically up-to-date advanced textbook is critical for both students and teachers. Norbert Sewald studied Chemistry at the Technical University of Munich, Germany, where he also obtained his PhD degree. The Nile on eBay   FREE SHIPPING UK WIDE   Peptides - Chemistry and Biology 2e by N. Sewald Thoroughly updated, incorporating around 25 # new material, Sewald/Jakubke remains the only modern and scientifically up-to-date advanced textbook on peptide biochemistry, distilling the knowledge of hundreds of publications into a highly readable synopsis of this diverse field. FORMATPaperback LANGUAGEEnglish CONDITIONBrand New Publisher Description Thoroughly updated, incorporating around 25 % new material, Sewald/Jakubke remains the only modern and scientifically up-to-date advanced textbook on peptide biochemistry, distilling the knowledge of hundreds of publications into a highly readable synopsis of this diverse field. The authors explain the broad fundamentals of peptide synthesis and structure, systematically addressing important families of biologically active peptides, and adopting an interdisciplinary approach that covers application areas in biotechnology, pharmaceutical science, and biomedicine. One major focus is on such "hot" research topics as pseudopeptides, peptidomimetics, and combinatorial synthesis.This new edition also features study questions for each learning unit, for easier self-study and classroom teaching. Back Cover With peptides playing such a valuable role in the body, the need for a modern and scientifically up-to-date advanced textbook is critical for both students and teachers. This book on peptide science distils the knowledge of hundreds of publications into a highly readable synopsis of this diverse field. Commencing with the broad fundamentals of peptide synthesis and structure, systematic explanations of the important families of biologically active peptides are given, and the interdisciplinary approach covers application areas in biotechnology, pharmaceutical science, and biomedicine. One major focus is on such "hot" research topics as pseudopeptides, peptidomimetics, combinatorial synthesis, and proteomics. This new edition has been fully revised and now features study questions and exercises for each learning unit, didactically enhanced for easier self-study and classroom teaching. Norbert Sewald studied Chemistry at the Technical University of Munich, Germany, where he also obtained his PhD degree. After postdoctoral work with J. E. Baldwin in Oxford, UK, he became an Assitant Professor at Leipzig University. Since 1999 he is full Professor at the University of Bielefeld where he holds the chair in Organic and Bioorganic Chemistry. His main scientific interest is in peptide chemistry, bioactive peptides., and their application in biochemistry and medical sciences. He has authored more than 120 publications and together with Hans-Dieter Jakubke, has written the book Peptides from A - Z, also published by Wiley-VCH. Hans-Dieter Jakubke studied Chemistry at the Martin-Luther-University Halle-Wittenberg, Germany. After finishing his PhD and postdoctoral work with Josef Rudinger in Prague (Czeck Republic), he was appointed Assistant Professor at the Department of Biochemistry in Halle, and Full Professor of Biochemistry at the University of Leipzig in 1977. He was director of the Department of Biochemistry from 1993-1997 and member of the Council of the European Peptide Society from 1990-1994. He authored several textbooks and encyclopedias on various aspects of chemistry and biochemistry including peptide research. Flap With peptides playing such a valuable role in the body, the need for a modern and scientifically up-to-date advanced textbook is critical for both students and teachers. This book on peptide science distils the knowledge of hundreds of publications into a highly readable synopsis of this diverse field. Commencing with the broad fundamentals of peptide synthesis and structure, systematic explanations of the important families of biologically active peptides are given, and the interdisciplinary approach covers application areas in biotechnology, pharmaceutical science, and biomedicine. One major focus is on such "hot" research topics as pseudopeptides, peptidomimetics, combinatorial synthesis, and proteomics. This new edition has been fully revised and now features study questions and exercises for each learning unit, didactically enhanced for easier self-study and classroom teaching. Norbert Sewald studied Chemistry at the Technical University of Munich, Germany, where he also obtained his PhD degree. After postdoctoral work with J. E. Baldwin in Oxford, UK, he became an Assitant Professor at Leipzig University. Since 1999 he is full Professor at the University of Bielefeld where he holds the chair in Organic and Bioorganic Chemistry. His main scientific interest is in peptide chemistry, bioactive peptides., and their application in biochemistry and medical sciences. He has authored more than 120 publications and together with Hans-Dieter Jakubke, has written the book Peptides from A - Z, also published by Wiley-VCH. Hans-Dieter Jakubke studied Chemistry at the Martin-Luther-University Halle-Wittenberg, Germany. After finishing his PhD and postdoctoral work with Josef Rudinger in Prague (Czeck Republic), he was appointed Assistant Professor at the Department of Biochemistry in Halle, and Full Professor of Biochemistry at the University of Leipzig in 1977. He was director of the Department of Biochemistry from 1993-1997 and member of the Council of the European Peptide Society from 1990-1994. He authored several textbooks and encyclopedias on various aspects of chemistry and biochemistry including peptide research. Author Biography Norbert Sewald studied Chemistry at the Technical University of Munich, Germany, where he also obtained his PhD degree. After postdoctoral work with J. E. Baldwin in Oxford, UK, he became an Assitant Professor at Leipzig University. Since 1999 he is full Professor at the University of Bielefeld where he holds the chair in Organic and Bioorganic Chemistry. His main scientific interest is in peptide chemistry, bioactive peptides., and their application in biochemistry and medical sciences. He has authored more than 120 publications and together with Hans-Dieter Jakubke, has written the book Peptides from A - Z, also published by Wiley-VCH. Hans-Dieter Jakubke studied Chemistry at the Martin-Luther-University Halle-Wittenberg, Germany. After finishing his PhD and postdoctoral work with Josef Rudinger in Prague (Czeck Republic), he was appointed Assistant Professor at the Department of Biochemistry in Halle, and Full Professor of Biochemistry at the University of Leipzig in 1977. He was director of the Department of Biochemistry from 1993-1997 and member of the Council of the European Peptide Society from 1990-1994. He authored several textbooks and encyclopedias on various aspects of chemistry and biochemistry including peptide research. Table of Contents INTRODUCTION AND BACKGROUNDFUNDAMENTAL CHEMICAL AND STRUCTURAL PRINCIPLESDefinitions and Main Conformational Features of the Peptide BondBuilding Blocks, Classification, and NomenclatureAnalysis of the Covalent Structure of Peptides and ProteinsThree-Dimensional StructureMethods of Structural AnalysisBIOLOGY OF PEPTIDESHistorical Aspects and Biological FunctionsBiosynthesisSelected Biologically Active PeptidesPEPTIDE SYNTHESISPrinciples and ObjectivesProtection of Functional GroupsPeptide Bond FormationRacemization During SynthesisSolid-Phase Peptide Synthesis (SPPS)Biochemical SynthesisSYNTHESIS CONCEPTS FOR PEPTIDES AND PROTEINSStrategy and TacticsSolution Phase Synthesis (SPS)NEW: Solution Phase/Solid Phase-Hybrid ApproachesOptimized Strategies on Polymeric SupportChemical Ligation StrategiesSYNTHESIS OF SPECIAL PEPTIDES AND PEPTIDE CONJUGATESCyclopeptidesCystine PeptidesGlycopeptidesPhosphopeptidesLipopeptidesSulfated PeptidesPEPTIDE AND PROTEIN DESIGN, PSEUDOPEPTIDES, AND PEPTIDOMIMETICSPeptide DesignModified PeptidesPeptidomimeticsPseudobiopolymersMacropeptides and De-Novo Design of Peptides and ProteinsCOMBINATORIAL PEPTIDE SYNTHESISParallel SynthesisSynthesis of MixturesAPPLICATION OF PEPTIDES AND PROTEINSNEW: General Production StrategiesNEW: Improvement of the Therapeutic PotentialProtein PharmaceuticalsPeptide PharmaceuticalsPEPTIDES IN PROTEOMICSNEW: Genome and ProteomeNEW: Separation MethodsNEW: Peptide and Protein Analysis in ProteomicsNEW: Activity-Based Proteomics Long Description With peptides playing such a valuable role in the body, the need for a modern and scientifically up-to-date advanced textbook is critical for both students and teachers. This book on peptide science distils the knowledge of hundreds of publications into a highly readable synopsis of this diverse field. Commencing with the broad fundamentals of peptide synthesis and structure, systematic explanations of the important families of biologically active peptides are given, and the interdisciplinary approach covers application areas in biotechnology, pharmaceutical science, and biomedicine. One major focus is on such "hot" research topics as pseudopeptides, peptidomimetics, combinatorial synthesis, and proteomics. This new edition has been fully revised and now features study questions and exercises for each learning unit, didactically enhanced for easier self-study and classroom teaching. Norbert Sewald studied Chemistry at the Technical University of Munich, Germany, where he also obtained his PhD degree. After postdoctoral work with J. E. Baldwin in Oxford, UK, he became an Assitant Professor at Leipzig University. Since 1999 he is full Professor at the University of Bielefeld where he holds the chair in Organic and Bioorganic Chemistry. His main scientifi, John Wiley & Sons<

2009, ISBN: 9783527318674

Softcover, 2nd revised updated edition. 578 pages. 9.50x7.00x1.50 inches., Neubuch, [PU: Vch Verlagsgesellschaft Mbh]

ISBN: 9783527318674

paperback, [PU: Wiley-VCH, Weinheim]