Schmerz - neues Buch

EAN (ISBN-13): 9783642595363
Erscheinungsjahr: 2013
Herausgeber: Springer-Verlag GmbH

Buch in der Datenbank seit 2017-06-04T08:48:22+02:00 (Berlin)
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ISBN/EAN: 9783642595363

ISBN - alternative Schreibweisen:
978-3-642-59536-3
Alternative Schreibweisen und verwandte Suchbegriffe:
Autor des Buches: brune, schäfer schäfer
Titel des Buches: der weg aus dem schmerz

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Daten vom Verlag:

Autor/in: K. Brune
Titel: Schmerz - Pathophysiologie — Pharmakologie — Therapie
Verlag: Springer; Springer Berlin
199 Seiten
Erscheinungsjahr: 2013-03-12
Berlin; Heidelberg; DE
Sprache: Deutsch
62,99 € (DE)

EA; E107; eBook; Nonbooks, PBS / Medizin/Klinische Fächer; Schmerz und Schmerztherapie; Verstehen; Analgetika; Neuropathischer Schmerz; Opiate; Opioid; Schmerzbehandlung; Schmerzpathophysiologie; Schmerzpharmakologie; Schmerztherapie; Tumorschmerz; B; Pain Medicine; Medicine; BC

Schmerz ist ein unangenehmes Sinnes- und Gefühlserlebnis, das mit aktueller oder potentieller Gewebeschädigung verknüpft ist oder mit den Begriffen einer solchen Schädigung beschrieben wird." So lautet die international gültige Definition des Phänomens Schmerz, dessen Pathophysiologie und Therapie Thema vieler Forschungsarbeiten ist und war. Das vorliegende Buch wendet sich vor allem an Ärzte in Klinik und Praxis, aber auch an fortgeschrittene Medizinstudenten, die einen Überblick über das Themengebiet Schmerz und vor allem die medikamentöse Schmerztherapie gewinnen wollen. Namhafte Experten haben das komplexe Thema aus drei Blickrichtungen bearbeitet: (1) Pathophysiologie des Schmerzes (2) Pharmakologie der Analgetika sowie anderer eingesetzter Pharmaka (3) Praktischer klinischer Teil mit Fallbeispielen Ein Glossar mit wichtigen Begriffen zur Schmerztherapie, eine Liste von Wirkstoffen und Handelsnamen sowie Hinweise auf weiterführende Literatur und eine Liste nützlicher Adressen vervollständigen das Buch. 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Wirkstoffen und Handelsnamen sowie Hinweise auf weiterführende Literatur und eine Liste nützlicher Adressen vervollständigen das Buch.";}}}i:1;a:2:{s:4:"NAME";s:11:"TextContent";s:5:"CHILD";a:3:{i:0;a:2:{s:4:"NAME";s:8:"TextType";s:5:"CDATA";s:2:"04";}i:1;a:2:{s:4:"NAME";s:15:"ContentAudience";s:5:"CDATA";s:2:"00";}i:2;a:3:{s:4:"NAME";s:4:"Text";s:5:"ATTRS";a:1:{s:10:"textformat";s:2:"06";}s:5:"CDATA";s:2514:"I Pathophysiologic des Schmerzes.- 1 Einleitung.- 1.1 Definition des Schmerzes.- 1.2 Konsequenzen des Schmerzes.- 1.3 Nozizeption und Schmerzwahrnehmung.- 2 Periphere Mechanismen.- 2.1 Umweltreize und sensorische Nervenfasern.- 2.2 Nozizeptoren.- 2.3 Transduktion: Kodierung von Schmerzreizen.- 2.4 Periphere Sensitivierung.- 2.5 Neurogene Entzündung.- 2.6 Nervenläsion: neuropathischer Schmerz.- 3 Zentrale Mechanismen.- 3.1 Transmission: zentrale Fortleitung von Schmerzimpulsen.- 3.2 Synaptische Übertragung.- 3.3 Zentrale Sensitivierung.- 4 Höhere Zentren.- 4.1 Perzeption: subkortikale und kortikale Schmerzzentren.- 4.2 Neuroplastizität der kortikalen Schmerzrepräsentation..- 5 Kontrollmechanismen des Schmerzes.- 5.1 Zentrale Kontrollmechanismen.- 5.2 Periphere Kontrollmechanismen.- 6 Schmerzmodulation durch Kälte, Wärme oder elektrische Stimulation.- 6.1 Kälte.- 6.2 Wärme.- 6.3 Elektrische Stimulation.- 7 Zusammenfassung.- II Angriffspunkte und Wirkungsmechanismen von Analgetika.- 8 Narkotische Analgetika (Opiate und Opioide).- 8.1 Geschichte der narkotischen Analgetika.- 8.2 Stoffeigenschaften.- 8.3 Pharmakodynamik (Wirkungen).- 8.4 Pharmakokinetik (Aufnahme, Verteilung, Elimination).- 8.5 Therapeutische Verwendung.- 8.6 Kombinierte Anwendung von narkotischen Analgetika mit anderen Wirkstoffen.- 8.7 Abhängigkeit, Sucht.- 9 Antipyretische Analgetika.- 9.1 Geschichte.- 9.2 Stoffeigenschaften.- 9.3 Pharmakodynamik Hemmung der Cyclooxygenase-Isoformen.- 9.4 Selektive Hemmung der Cyclooxygenase (COX-2).- 9.5 Funktionen der Cyclooxygenase-Isoformen.- 9.6 Prostaglandine als Mediatoren der Hyperalgesie.- 9.7 Prostaglandine als Mediatoren der Fieberentstehung.- 9.8 Pharmakokinetik (Aufnahme, Verteilung, Elimination, Arzneimittelinteraktionen).- 9.9 AnalgetischeMischpräparate.- 10 Nichtopioidanalgetika ohne antipyretische und antiphlogistische Wirkung: Flupirtin, Ketamin und Nefopam.- 10.1 Stoffeigenschaften.- 10.2 Pharmakodynamik.- 10.3 Pharmakokinetik.- 10.4 Therapeutische Verwendung.- 11 Antidepressiva.- 12 Serotoninagonisten.- 13 Antikonvulsiva.- 14 Antihistaminika.- 15 Lokalanästhetika.- 16 Neuroleptika.- 17 Glukokortikoide.- III Therapie.- 18 Schmerzen im Bereich der Wirbelsäule.- 19 Neurogene Schmerzen.- 20 Kopf-und Gesichtsschmerz.- 21 Rheumatischer Schmerz.- 22 Tumorschmerz.- 23 Akuter/Postoperativer Schmerz.- 24 Viszeraler Schmerz.- 25 Fibromyalgie.- 26 Psychotherapeutische Aspekte.- 27 Patientenführung bei chronisch Schmerzkranken.- Stichwortverzeichnis.";}}}i:2;a:2:{s:4:"NAME";s:11:"TextContent";s:5:"CHILD";a:3:{i:0;a:2:{s:4:"NAME";s:8:"TextType";s:5:"CDATA";s:2:"05";}i:1;a:2:{s:4:"NAME";s:15:"ContentAudience";s:5:"CDATA";s:2:"00";}i:2;a:3:{s:4:"NAME";s:4:"Text";s:5:"ATTRS";a:1:{s:10:"textformat";s:2:"06";}s:5:"CDATA";s:1237:"Schmerz ist ein unangenehmes Sinnes- und Gefühlserlebnis, das mit aktueller oder potentieller Gewebeschädigung verknüpft ist oder mit den Begriffen einer solchen Schädigung beschrieben wird." So lautet die international gültige Definition des Phänomens Schmerz, dessen Pathophysiologie und Therapie Thema vieler Forschungsarbeiten ist und war. Das vorliegende Buch wendet sich vor allem an Ärzte in Klinik und Praxis, aber auch an fortgeschrittene Medizinstudenten, die einen Überblick über das Themengebiet Schmerz und vor allem die medikamentöse Schmerztherapie gewinnen wollen. Namhafte Experten haben das komplexe Thema aus drei Blickrichtungen bearbeitet: (1) Pathophysiologie des Schmerzes (2) Pharmakologie der Analgetika sowie anderer eingesetzter Pharmaka (3) Praktischer klinischer Teil mit Fallbeispielen Ein Glossar mit wichtigen Begriffen zur Schmerztherapie, eine Liste von Wirkstoffen und Handelsnamen sowie Hinweise auf weiterführende Literatur und eine Liste nützlicher Adressen vervollständigen das Buch. 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