It has been known for half a century that neurotransmitters are released in preformed quanta, that the quanta represent transmitter-storing vesicles, and that release occurs by exocytosis… Mehr…
It has been known for half a century that neurotransmitters are released in preformed quanta, that the quanta represent transmitter-storing vesicles, and that release occurs by exocytosis. The focus of this book is twofold. In the first part, the molecular events of exocytosis are analysed. This includes a discussion of presynaptic calcium channels, the core proteins of the secretory machinery, and the actions of clostridial toxins and a -latrotoxin, famous for their potency as well as their crucial role in the elucidation of the steps of exocytosis. In the bookâ??s second part, the presynaptic receptors for endogenous chemical signals are presented that make neurotransmitter release a highly regulated process. These include ligand-gated ion channels and presynaptic G-protein-coupled receptors. The targets of presynaptic receptors within the exocytosis cascade, and their therapeutic potential, are subjects addressed in the majority of chapters. Books > Biomedicine Soft cover, Springer Shop<
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It has been known for half a century that neurotransmitters are released in preformed quanta, that the quanta represent transmitter-storing vesicles, and that release occurs by exocytosis… Mehr…
It has been known for half a century that neurotransmitters are released in preformed quanta, that the quanta represent transmitter-storing vesicles, and that release occurs by exocytosis. The focus of this book is twofold. In the first part, the molecular events of exocytosis are analysed. This includes a discussion of presynaptic calcium channels, the core proteins of the secretory machinery, and the actions of clostridial toxins and a -latrotoxin, famous for their potency as well as their crucial role in the elucidation of the steps of exocytosis. In the bookâ??s second part, the presynaptic receptors for endogenous chemical signals are presented that make neurotransmitter release a highly regulated process. These include ligand-gated ion channels and presynaptic G-protein-coupled receptors. The targets of presynaptic receptors within the exocytosis cascade, and their therapeutic potential, are subjects addressed in the majority of chapters. Books > Biomedicine Soft cover, Springer Shop<
new in stock. Versandkosten:zzgl. Versandkosten. (EUR 0.00)
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It has been known for half a century that neurotransmitters are released in preformed quanta, that the quanta represent transmitter-storing vesicles, and that release occurs by exocytosis. The focus of this book is twofold. In the first part, the molecular events of exocytosis are analysed. In the second part of the book, the presynaptic receptors for endogenous chemical signals are presented that make neurotransmitter release a highly regulated process.
Detailangaben zum Buch - Pharmacology of Neurotransmitter Release
EAN (ISBN-13): 9783642094248 ISBN (ISBN-10): 3642094244 Gebundene Ausgabe Taschenbuch Erscheinungsjahr: 2010 Herausgeber: Springer Berlin 596 Seiten Gewicht: 0,888 kg Sprache: eng/Englisch
Buch in der Datenbank seit 2011-03-25T12:08:02+01:00 (Berlin) Detailseite zuletzt geändert am 2022-10-07T09:37:46+02:00 (Berlin) ISBN/EAN: 9783642094248
ISBN - alternative Schreibweisen: 3-642-09424-4, 978-3-642-09424-8 Alternative Schreibweisen und verwandte Suchbegriffe: Autor des Buches: südhof thomas, stark, starke, sta, klaus thoma Titel des Buches: pharmacology, release
Daten vom Verlag:
Autor/in: Thomas C. Südhof; Klaus Starke Titel: Handbook of Experimental Pharmacology; Pharmacology of Neurotransmitter Release Verlag: Springer; Springer Berlin 582 Seiten Erscheinungsjahr: 2010-11-22 Berlin; Heidelberg; DE Gedruckt / Hergestellt in Niederlande. Sprache: Englisch 213,99 € (DE) 219,99 € (AT) 236,00 CHF (CH) POD XIV, 582 p.
Neurotransmitter Release.- Pharmacology of Neurotransmitter Release: Measuring Exocytosis.- Presynaptic Calcium Channels: Structure, Regulators, and Blockers.- Pharmacology of Neurotransmitter Transport into Secretory Vesicles.- Core Proteins of the Secretory Machinery.- Presynaptic Neurotoxins with Enzymatic Activities.- ?-Latrotoxin and Its Receptors.- Presynaptic Signaling by Heterotrimeric G-Proteins.- Presynaptic Metabotropic Receptors for Acetylcholine and Adrenaline/Noradrenaline.- Presynaptic Receptors for Dopamine, Histamine, and Serotonin.- Presynaptic Adenosine and P2Y Receptors.- Presynaptic Metabotropic Glutamate and GABA B Receptors.- Presynaptic Neuropeptide Receptors.- Presynaptic Modulation by Endocannabinoids.- Presynaptic lonotropic Receptors.- NO/cGMP-Dependent Modulation of Synaptic Transmission.- Therapeutic Use of Release-Modifying Drugs. Includes supplementary material: sn.pub/extras
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