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The ability to introduce non-canonical amino acids in vivo has greatly expanded the repertoire of accessible proteins for basic research and biotechnological application. Here, the differ… Mehr…

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Nediljko Budisa (Max-Planck-Institute of Biochemistry, Martinsried, Germany):
Engineering the Genetic Code: Expanding the Amino Acid Repertoire for the Design of Novel Proteins Format: Hardcover - gebunden oder broschiert

2005, ISBN: 3527312439

[EAN: 9783527312436], Neubuch, [PU: John Wiley and Sons], Brand New, Books

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Nediljko Budisa:
Engineering the Genetic Code - Erstausgabe

2005, ISBN: 9783527312436

Gebundene Ausgabe

Expanding the Amino Acid Repertoire for the Design of Novel Proteins, Buch, Hardcover, 1. Auflage, [PU: Wiley-VCH], Wiley-VCH, 2005

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Details zum Buch
Engineering the Genetic Code: Expanding the Amino Acid Repertoire for the Design of Novel Proteins Nediljko Budisa Author
Autor:
Titel:
ISBN-Nummer:

9783527312436


The ability to introduce non-canonical amino acids in vivo has greatly expanded the repertoire of accessible proteins for basic research and biotechnological application. Here, the different methods and strategies to incorporate new or modified amino acids are explained in detail, including a lot of practical advice for first-time users of this powerful technique. Novel applications in protein biochemistry, genomics, biotechnology and biomedicine made possible by the expansion of the genetic code are discussed and numerous examples are given. Essential reading for all molecular life scientists who want to stay ahead in their research.

Detailangaben zum Buch - Engineering the Genetic Code: Expanding the Amino Acid Repertoire for the Design of Novel Proteins Nediljko Budisa Author


EAN (ISBN-13): 9783527312436
ISBN (ISBN-10): 3527312439
Gebundene Ausgabe
Erscheinungsjahr: 2005
Herausgeber: Wiley Core >2 >T
296 Seiten
Gewicht: 0,722 kg
Sprache: eng/Englisch

Buch in der Datenbank seit 2007-04-17T11:15:56+02:00 (Berlin)
Detailseite zuletzt geändert am 2024-03-10T14:43:35+01:00 (Berlin)
ISBN/EAN: 9783527312436

ISBN - alternative Schreibweisen:
3-527-31243-9, 978-3-527-31243-6
Alternative Schreibweisen und verwandte Suchbegriffe:
Titel des Buches: acid, proteins, design engineering, repertoire, engineering the genetic code, budissa, code zdf

Daten vom Verlag:

Autor/in: Nediljko Budisa
Titel: Engineering the Genetic Code - Expanding the Amino Acid Repertoire for the Design of Novel Proteins
Verlag: Wiley-VCH; Wiley-VCH
296 Seiten
Erscheinungsjahr: 2005-10-26
Gedruckt / Hergestellt in Deutschland.
Gewicht: 0,738 kg
Sprache: Englisch
225,20 € (DE)
170mm x 240mm x 20mm

BB; Hardcover, Softcover / Chemie/Organische Chemie; Biochemie; Verstehen; Aminosäuren; Biochemie; Biochemie u. Chemische Biologie; Biochemistry (Chemical Biology); Biomedical Engineering; Biomedizintechnik; Biotechnologie; Biowissenschaften; Cell & Molecular Biology; Chemie; Chemistry; Genetics; Genetik; Life Sciences; Protein Engineering; Protein-Engineering; Proteinsynthese; Zell- u. Molekularbiologie; Protein-Engineering; Biochemie u. Chemische Biologie; Zell- u. Molekularbiologie; Genetik

The chemistry of the life is based on defined number of the generic monomeric building blocks. For example, twenty canonical alpha-amino acids are encoded for basic protein syntheses in all organisms. The central issue of this book are experimental strategies and techniques to expand the number of the amino acids for protein biosyntheses. This requires the reprogramming of protein translation machinery by changing the coding capacities of standard genetic code - a main goal of the genetic code engineering as new research field. Such genetically encoded protein modifications achieved by introducing non-canonical amino acids both in vitro and in vivo have greatly expanded the repertoire of accessible proteins for basic research and biotechnological application. The researchers and students are provided with a comprehensive coverage of important new principles of different methods and strategies to incorporate new or modified amino acids into proteins including a lot of practical advice for first-time users of these powerful approaches. Numerous examples, made possible by the expansion of the genetic code, are given in order to cover the entire spectrum of novel applications in protein biochemistry, genomics, biotechnology and biomedicine. Some other interesting aspects discussed in this book include the relations between prebiotic (extraterrestrial, meteoritic, interstellar) and encoded amino acids; the possibility to couple engineered metabolic circuits with reprogrammed translation; to remodel current life and progressively develop truly novel life forms, as well as possible ethical implications of such experiments on human societies. Essential reading for all molecular life scientists who want to stay ahead in their research.

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