Vanadium Compounds: Biochemical and Therapeutic Applications - neues Buch

EAN (ISBN-13): 9781461312512
Erscheinungsjahr: 2012
Herausgeber: Springer US

Buch in der Datenbank seit 2016-12-01T23:08:10+01:00 (Berlin)
Detailseite zuletzt geändert am 2023-06-06T14:17:48+02:00 (Berlin)
ISBN/EAN: 9781461312512

ISBN - alternative Schreibweisen:
978-1-4613-1251-2
Alternative Schreibweisen und verwandte Suchbegriffe:
Autor des Buches: srivastava, chiasson, günther
Titel des Buches: vanadium

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Daten vom Verlag:

Autor/in: Ashok K. Srivastava; Jean-Louis Chiasson
Titel: Developments in Molecular and Cellular Biochemistry; Vanadium Compounds: Biochemical and Therapeutic Applications
Verlag: Springer; Springer US
246 Seiten
Erscheinungsjahr: 2012-12-06
New York; NY; US
Sprache: Englisch
96,29 € (DE)
99,00 € (AT)
118,00 CHF (CH)
Available
VI, 246 p. 5 illus.

EA; E107; eBook; Nonbooks, PBS / Medizin/Klinische Fächer; Endokrinologie; Verstehen; Diabetes; Diabetes mellitus; Pancreas; homeostasis; insulin; insulin-like; signal transduction; C; Endocrinology; Diseases; Medical Biochemistry; Biomedical and Life Sciences; Krankheiten und Störungen; Medizinische Chemie, Pharmazeutische Chemie; BC

I: Chemistry.- The chemistry of peroxovanadium compounds relevant to insulin mimesis.- Vanadium chemistry and biochemistry of relevance for use of vanadium compounds as antidiabetic agents.- Peroxo heteroligand vanadates(V): Synthesis, spectra-structure relationships, and stability toward decomposition.- Chemically and photochemically initiated DNA cleavage by an insulin-mimetic bisperoxovanadium complex.- II: Biochemical and physiological studies.- Insulin-like actions of vanadate are mediated in an insulin-receptor-independent manner via non-receptor protein tyrosine kinases and protein phosphotyrosine phosphatases.- Peroxovanadium compounds: Biological actions and mechanism of insulin-mimesis.- Unique and selective mitogenic effects of vanadate on SV40-transformed cells.- Vanadium salts stimulate mitogen-activated protein (MAP) kinases and ribosomal S6 kinases.- Protective effect of vanadate on oxyradical-induced changes in isolated perfused heart.- In vivo effects of vanadate on hepatic glycogen metabolizing and lipogenic enzymes in insulin-dependent and insulin-resistant diabetic animals.- The relationship between insulin and vanadium metabolism in insulin target tissues.- Modulation of insulin action by vanadate: Evidence of a role for phosphotyrosine phosphatase activity to alter cellular signaling.- Reversal of defective G-proteins and adenylyl cyclase/cAMP signal transduction in diabetic rats by vanadyl sulphate therapy.- Effects of vanadate on the expression of genes involved in fuel homeostasis in animal models of Type I and Type II diabetes.- Decrease in protein tyrosine phosphatase activities in vanadate-treated obese Zucker (fa/fa) rat liver.- Evidence for selective effects of vanadium on adipose cell metabolism involving actions on cAMP-dependent proteinkinase.- The enhancement by pervanadate of tyrosine phosphorylation on prostatic proteins occurs through the inhibition of membrane-associated tyrosine phosphatases.- Contractile effects of vanadate on aorta rings from virgin and pregnant rats.- In vivo modulation of N-myristoyltransferase activity by orthovanadate.- Regulation and control of glucose overutilization in erythrocytes by vanadate.- In vitro and in vivo antineoplastic effects of ortrovanadate.- Membrane — vanadium interaction: A toxicokinetic evaluation.- III: Potential use in therapy and toxicological studies.- Increased potency of vanadium using organic ligands.- In vivo effects of peroxovanadium compounds in BB rats.- Long-term antidiabetic activity of vanadyl after treatment withdrawal: Restoration of insulin secretion?.- Long-term correction of STZ-diabetic rats after short-term i.p. VOSO4 treatment: Persistence of insulin secreting capacities assessed by isolated pancreas studies.- Antihypertensive effects of vanadium compounds in hyperinsulinemic, hypertensive rats.- Vanadate induces normolipidemia and a reduction in the levels of hepatic iipogenic enzymes in obese Zucker rat.- In vivo and in vitro studies of vanadate in human and rodent diabetes mellitus.- Toxicology of vanadium compounds in diabetic rats: The action of chelating agents on vanadium accumulation.- Index to Volume 153.