ISBN: 9780387894560

Currently,there is no single source that permitscomparisonof the factors, elements, enzymes and/or mechanisms employed by different classes of viruses for genome replication. As a result,… Mehr…

Currently,there is no single source that permitscomparisonof the factors, elements, enzymes and/or mechanisms employed by different classes of viruses for genome replication. As a result, we (and our students) often restrict our focus to our parti- lar system,missing outon theopportunityto de neunifyingthemesin viralgenome replication or bene t from the advances in other systems. For example, extraor- nary biologicaland experimentalparadigmsthat have been established overthe past 5 years for the DNA replication systems of bacteriophage T4 will likely be of great value to anyone interested in studying a replisome from any virus. These studies could easily go unnoticed by animal RNA and DNA virologists. It is our hope that this monograph will cross-fertilize and invigorate the eld, as well as encourage students into this area of research. The monograph has been divided into eight parts. Chapters appearing in Parts I-VI are intended to compare and contrast the replication and/or transcription processes and corresponding 'players' of the indicated family of viruses. We are interested in the sequence of events that lead to production of mRNA and progeny genomes as well as the cis-acting elements and trans-acting factors and enzymes (viral and cellular) that are required for these processes. Chapters appearing in Part VII are - tended to providea more biochemical and biophysicalperspective of the replication and/ortranscriptionprocess. Chaptersappearingin Part VIII are intendedto provide a practical perspective on viral replication and its inhibition. eBooks > Fremdsprachige eBooks > Englische eBooks > Sach- & Fachthemen > Medizin; eBooks > Fremdsprachige eBooks > Englische eBooks > Sach- & Fachthemen > Biologie; eBooks > Fachbücher > Medizin; eBooks > Fachbücher > Biowissenschaften , Springer, Springer<

2009, ISBN: 9780387894560

Currently,there is no single source that permitscomparisonof the factors, elements, enzymes and/or mechanisms employed by different classes of viruses for genome replication. As a result,… Mehr…

Currently,there is no single source that permitscomparisonof the factors, elements, enzymes and/or mechanisms employed by different classes of viruses for genome replication. As a result, we (and our students) often restrict our focus to our parti- lar system,missing outon theopportunityto de neunifyingthemesin viralgenome replication or bene t from the advances in other systems. For example, extraor- nary biologicaland experimentalparadigmsthat have been established overthe past 5 years for the DNA replication systems of bacteriophage T4 will likely be of great value to anyone interested in studying a replisome from any virus. These studies could easily go unnoticed by animal RNA and DNA virologists. It is our hope that this monograph will cross-fertilize and invigorate the eld, as well as encourage students into this area of research. The monograph has been divided into eight parts. Chapters appearing in Parts I-VI are intended to compare and contrast the replication and/or transcription processes and corresponding 'players' of the indicated family of viruses. We are interested in the sequence of events that lead to production of mRNA and progeny genomes as well as the cis-acting elements and trans-acting factors and enzymes (viral and cellular) that are required for these processes. Chapters appearing in Part VII are - tended to providea more biochemical and biophysicalperspective of the replication and/ortranscriptionprocess. Chaptersappearingin Part VIII are intendedto provide a practical perspective on viral replication and its inhibition. eBook Springer PDF, Springer, 28.05.2009, Springer, 2009<

2009, ISBN: 9780387894560

Viruses are responsible for a variety of human, animal, and plant diseases and now represent potential agents of terror. Academic, government, and corporate laboratories have devoted year… Mehr…

Viruses are responsible for a variety of human, animal, and plant diseases and now represent potential agents of terror. Academic, government, and corporate laboratories have devoted years of effort to the development of strategies to prevent or treat viral infections. Central to the multiplication strategy of all viruses is the process of genome replication. Enzymes critical to this step of the lifecycle have proven to be tractable targets for the development of antiviral agents. Furthermore, genome replication is essential for virus spread and is the main target for the development of antiviral agents. By combining studies of both RNA and DNA viruses - and more - into a single volume, the editors have created a mechanism for cross-talk between the fields that will produce synergy and could lead to more rapid discovery of approaches to treat viral infections. eBook Springer PDF, Springer, 28.05.2009, Springer, 2009<

2009, ISBN: 9780387894560

Viruses are responsible for a variety of human, animal, and plant diseases and now represent potential agents of terror. Academic, government, and corporate laboratories have devoted year… Mehr…

Viruses are responsible for a variety of human, animal, and plant diseases and now represent potential agents of terror. Academic, government, and corporate laboratories have devoted years of effort to the development of strategies to prevent or treat viral infections. Central to the multiplication strategy of all viruses is the process of genome replication. Enzymes critical to this step of the lifecycle have proven to be tractable targets for the development of antiviral agents. Furthermore, genome replication is essential for virus spread and is the main target for the development of antiviral agents. By combining studies of both RNA and DNA viruses - and more - into a single volume, the editors have created a mechanism for cross-talk between the fields that will produce synergy and could lead to more rapid discovery of approaches to treat viral infections. eBook Springer 28.05.2009, Springer, Springer<

2009, ISBN: 9780387894560

eBooks, eBook Download (PDF), 2009, [PU: Springer US], Springer US, 2009