Women can be described as genetic mosaics because they have two distinctly different types of cells throughout their bodies. Unlike males, who have one X chromosome (inherited from their … Mehr…
Women can be described as genetic mosaics because they have two distinctly different types of cells throughout their bodies. Unlike males, who have one X chromosome (inherited from their mother), females have two X chromosomes in every cell (one from each parent). The fathers copy works in some cells, while the mothers copy works in others. These two X chromosomes often function differently, especially if one carries a defective gene. Much has been written about the Y chromosome and its role in inducing maleness. This will be the first book about the X chromosome as a key to female development and the role of X-related factors in the etiology of sex differences in human disease. Barbara Migeon, from the renowned McKusick-Nathan Institute at Johns Hopkins, is a major figure in clinical genetics and is eminently qualified to write this book, and she writes clearly and effectively. She describes both the underlying molecular mechanisms and the remarkable genetic consequences of X inactivation and its role in determining the biological concepts characteristic of women. Females are Mosaics will be valuable to geneticists, biologists, and all health professionals interested in women's health. Medicine Medicine eBook, Oxford University Press, USA<
[EAN: 9780195188127], [PU: Oxford University Press], Medical|Genetics, This Book is in Good Condition. Clean Copy With Light Amount of Wear. 100% Guaranteed. Summary: Introduction. Sectio… Mehr…
[EAN: 9780195188127], [PU: Oxford University Press], Medical|Genetics, This Book is in Good Condition. Clean Copy With Light Amount of Wear. 100% Guaranteed. Summary: Introduction. Section I. Background. 1. Sex Differences in Disease2. Evolution of the Human Sex Chromosomes and a Portrait of the Human X3. Overview: X Chromosome Dosage Compensation4. The Discovery of X Chromosome Inactivation and the Lyon Hypothesis5. Experimental Models for X Inactivation StudiesSection II. Themes and Variations. 6. Theme 1: The Initial Steps: Creating the Active and Inactive X7. Theme 2: The Subsequent Steps: Spreading Silence Along the X and Maintaining It8. Variations 1: Stability of the Inactive X9. Variations 2: Choice of Active XSection III. Medical Consequences. 10. Medical Consequence 1: The Single Active X11. Medical Consequence 2: Cellular Mosaicism12. Determinants of Female PhenotypesReferences. List of Tables. Glossary. Index.<
Women can be described as genetic mosaics because they have two distinctly different types of cells throughout their bodies. Unlike males, who have one X chromosome (inherited from their … Mehr…
Women can be described as genetic mosaics because they have two distinctly different types of cells throughout their bodies. Unlike males, who have one X chromosome (inherited from their mother), females have two X chromosomes in every cell (one from each parent). The fathers copy works in some cells, while the mothers copy works in others. These two X chromosomes often function differently, especially if one carries a defective gene. Much has been written about the Y chromosome and its role in inducing maleness. This will be the first book about the X chromosome as a key to female development and the role of X-related factors in the etiology of sex differences in human disease. Barbara Migeon, from the renowned McKusick-Nathan Institute at Johns Hopkins, is a major figure in clinical genetics and is eminently qualified to write this book, and she writes clearly and effectively. She describes both the underlying molecular mechanisms and the remarkable genetic consequences of X inactivation and its role in determining the biological concepts characteristic of women. Females are Mosaics will be valuable to geneticists, biologists, and all health professionals interested in women's health. Medicine Medicine eBook, Oxford University Press, USA<
[EAN: 9780195188127], [PU: Oxford University Press], Medical|Genetics, This Book is in Good Condition. Clean Copy With Light Amount of Wear. 100% Guaranteed. Summary: Introduction. Sectio… Mehr…
[EAN: 9780195188127], [PU: Oxford University Press], Medical|Genetics, This Book is in Good Condition. Clean Copy With Light Amount of Wear. 100% Guaranteed. Summary: Introduction. Section I. Background. 1. Sex Differences in Disease2. Evolution of the Human Sex Chromosomes and a Portrait of the Human X3. Overview: X Chromosome Dosage Compensation4. The Discovery of X Chromosome Inactivation and the Lyon Hypothesis5. Experimental Models for X Inactivation StudiesSection II. Themes and Variations. 6. Theme 1: The Initial Steps: Creating the Active and Inactive X7. Theme 2: The Subsequent Steps: Spreading Silence Along the X and Maintaining It8. Variations 1: Stability of the Inactive X9. Variations 2: Choice of Active XSection III. Medical Consequences. 10. Medical Consequence 1: The Single Active X11. Medical Consequence 2: Cellular Mosaicism12. Determinants of Female PhenotypesReferences. List of Tables. Glossary. Index.<
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Talks about the X chromosome as a key to female development and the role of X-related factors in the etiology of sex differences in human disease. This book describes both the underlying molecular mechanisms and the remarkable genetic consequences of X inactivation and its role in determining the biological concepts characteristic of women.
Detailangaben zum Buch - Females Are Mosaics: X Inactivation and Sex Differences in Disease
Buch in der Datenbank seit 2008-01-05T15:39:56+01:00 (Berlin) Detailseite zuletzt geändert am 2022-12-07T19:41:38+01:00 (Berlin) ISBN/EAN: 9780195188127
ISBN - alternative Schreibweisen: 0-19-518812-8, 978-0-19-518812-7 Alternative Schreibweisen und verwandte Suchbegriffe: Autor des Buches: migeon Titel des Buches: mosaic, females mosaics inactivation sex differences disease, sex ics
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